Volume 35, Issue 135 (April 2022)                   IJN 2022, 35(135): 76-93 | Back to browse issues page

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Kheirkhah M, Ahadi A, Nabavi S M, Tavakkol N, Lotfi T. Evaluation the Effect of the Health Promoting Lifestyle by Multimedia Education on Sexual Function in Women With Multiple Sclerosis. IJN 2022; 35 (135) :76-93
URL: http://ijn.iums.ac.ir/article-1-3477-en.html
1- Department of Midwifery and Reproduction Health, Faculty of Nursing and Midwifery, Iran University of Medical Sciences, Tehran, Iran. , kheirkhah.m@iums.ac.ir
2- Department of Midwifery and Reproduction Health, Faculty of Nursing and Midwifery, Iran University of Medical Sciences, Tehran, Iran.
3- Department of Brain and Cognitive Sciences, Institute of Biology and Technology of Stem Cells, Jihad University, Tehran, Iran.
4- Porsina Hakim Gastrointestinal Diseases Research Center, Isfahan University of Medical Sciences, Isfahan, Iran.
5- Rasoul Akram Clinical Research Development Center, Iran University of Medical Sciences, Tehran, Iran.
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Multiple sclerosis is the most common progressive neurological disease in young people, affecting women several times more than men. Sexual problems are one of the most common symptoms in women with multiple sclerosis that is often neglected. The main aim of this study is evaluate the effect of health promoting lifestyle (HPL) education in multimedia method on the sexual function of women with Multiple Sclerosis.

Materials and Methods
The present study is a randomized controlled trial of before and after with the control group. 116 women with multiple sclerosis with inclusion criteria, referredto Hazrat Rasool Akram Hospital and a private referral center for multiple sclerosis patients (from 21 September 2020 to 19 January 2021) were selected by continues sampling method to participate in the study. They were assigned as two groups, intervention and control ones, using the Sealed envelope randomized online site which randomly divided to single up to quintuple blocks, which allocated equally in intervention and control groups. After providing a description of objectives and methods of the study, the informed written consent (for those who were invited to study by phone was sent and completed electronically) was completed by the participants. Data collection tools were demographic profile form and intimacy and sexual activity questionnaire for multiple sclerosis patients (MSISQ-19), which were completed three times before, immediately after training (4 weeks after the start of the study) and after the follow-up period (12 weeks after the start of the study) completed. The second and third times of completing the questionnaires were electronic. After completing the questionnaires for the first time, multimedia HPL training with multimedia in 4 sessions of 40 minutes, one session per week was provided for the intervention group. During the training and follow-up period, the researcher answered the participants’ questions during a telephone call and providing a brief description of the training on the topic of that week. Data analysis is done by using descriptive statistical methods (mean, standard deviation, frequency and percentage) and with independent t-test, chi-square, analysis of covariance and analysis of variance with repeated measures RM using SPSS software v. 16.

Independent t-test results showed pre-intervention between sexual function scores (P=0.690) and all its dimensions (primary P=0.117; secondary P=0.053; tertiary P=0.287) there was no significant difference between the two groups. The results of analysis of variance with repeated measures showed that the scores of sexual function (P=0.431) and all its dimensions (primary P=0.362, secondary P=0.915; tertiary P=0.168). There was no significant difference in time in the control group. Butin the intervention group, sexual function scores (P<0.001) and primary dimensions (P=0.003) and secondary (P<0.001) had a significant difference in at least one of the times. The results of Bonferroni correction test showed that the scores of sexual dysfunction in primary, secondary and total scores of sexual function in 4 weeks and 12 weeks after the intervention were significantly lower than before (P<0.050). There was no statistically significant difference between 4 weeks and 12 weeks after the intervention (P>0.050). To evaluate the effect of the intervention, Partial ƞ2 was used, which according to Cohen’s classification is considered as small (0.01), medium (0.06) and high (0.14) effect. The effect size of sexual function was equal to 0.143 and the maximum effect on sexual function was in the secondary dimension (0.216) and the lowest effect was in the primary dimension of sexual function (0.105). The results of analysis of covariance showed that sexual dysfunction in the primary dimension (P=0.019) in the intervention group in 4 weeks after the intervention and sexual function in the secondary dimension 4 weeks after the intervention (P=0.026) and 12 weeks later in the intervention group (P=0.013) was significantly lower than the control group. But there was no significant difference between the scores of tertiary sexual function at 4 weeks (P=0.249) and at 12 weeks (P=0.089) between the two groups. The total score of sexual function 4 weeks after the intervention (P=0.014) and 12 weeks after the intervention (P=0.021) in the intervention group was significantly lower than the control group. 
The results of covariance test showed that before the intervention, there was a significant difference between the two groups in the sexual dysfunction (P<0.001). Many items of female sexual function in the intervention group immediately after the intervention and the follow-up period improved. . In the initial dimension of intervention in items with late orgasm,the intensity or low pleasure of orgasm was significant and the highest effect was related to the item of late orgasm (0.176). In the secondary dimension, intervention in pain or burning items, intestinal problems, urinary problems, concentration, memory and thinking problems were significant and the highest effect was related to body pain or burning items (0.152). There was no difference between the groups in the third dimension

According to the findings of this study, HPL education affects the sexual function of women with multiple sclerosis. Therefore, a HPL can be a good way to improve the sexual problems of these women. Training in this study was done using multimedia, which was cost-effective and cost-effective compared to face-to-face methods, and was considered a safe method, especially in the context of the study due to the presence of the corona epidemic. Due to the possibility of repeated use of education at the desired times and places and places have a high impact on the limited time of the study, due to the simultaneous use of multimedia and engaging multiple senses of the body in education, learning faster, deeper and easier wetness and durability has had a greater effect on the learner than what has been learned. It is recommended that physicians, midwives and other sexual health therapists use this method, which is low cost and does not require patient traffic and can be used at any time and place. Officials and therapists of the Multiple Sclerosis Association can use this method along with other methods to reduce the sexual problems of these patients. The absence of the spouses of the women participating in the study and their lack of education, which can be an obstacle to effective communication between the couples, is a limitation of the study to evaluate the sexual function of women with multiple sclerosis.

Ethical Considerations
Ethical permission for this study has been obtained from the ethics committee of Iran University of Medical Sciences with the code IR.IUMS.REC.1399.367 and has been registered in the Iranian Clinical Trial Center (IRCT2016061528449N4).

All authors contributed equally in preparing all parts of the research.

Authors' contributions
Research and article writing: Masoumeh Khairkhah and Azadeh Ahadi; Doing statistical affairs of the research: Najmeh Tavakol; Sampling: Massoud Nabavi and Lotfi.

Conflict of interest
The authors declared no conflict of interest.

Researchers from the Vice Chancellor for Research and Postgraduate Studies of Iran University of Medical Sciences and officials of the School of Nursing and Midwifery of Iran University of Medical Sciences, all women participating in the study, all officials and staff of Rasool Akram Hospital, especially internal neurology clinic We thank the private neurology clinic located in Tehran and all those who helped us in this research.

  1. Jameson JL, Fauci AS, Kasper DL, Hauser SL, Longo DL, Loscalzo J. Harrison’s principles of internal medicine. New York: McGraw-Hill Education; 2018. [Link]
  2. Zarabadipour S, Amini L, Nabavi SM, Haghani H. [Menstrual disorders and related factors in women with multiple sclerosis (Persian)]. Iran J Obstet Gynecol Infertil. 2018; 21(4):43-52. [DOI:10.22038/IJOGI.2018.11226]
  3. World Health Organization, Multiple Sclerosis International Federation. Atlas: Multiple sclerosis resources in the world 2008. Geneva: World Health Organization; 2008. https://apps.who.int/iris/handle/10665/43968
  4. Miletta M, Bogliatto F, Bacchio L. Multidisciplinary management of sexual dysfunction, perineal pain, and elimination dysfunction in a woman with multiple sclerosis. Int J MS Care. 2017; 19(1):25-8. [DOI:10.7224/1537-2073.2015-082] [PMID] [PMCID]
  5. Tajikesmaeili A, Hakim Abadim G. [Sexual functions and marital adjustment married woman with Multiple Sclerosis (Persian)]. Res Psychol Health. 2016: 10(2):1-9. [Link]
  6. Kooranian F, Foroughipour M, Khosravi A. [Association of disability with urinary and sexual dysfunction in patients with multiple sclerosis (Persian)]. Iran J Obstet Gynecol Infertil. 2018; 20(11):39-46. [DOI:10.22038/IJOGI.2018.10226]
  7. Ghasemi V, Simbar M, Ozgoli G, Nabavi SM, Alavi Majd H, Mohammad Souri B, et al. The prevalence of sexual dysfunction in Iranian women with multiple sclerosis: A systematic review and meta-analysis. Shiraz E-Med J. 2019; 20(6):e83490. [DOI:10.5812/semj.83490]
  8. Merghati-Khoei E, Qaderi K, Amini L, Korte JE. Sexual problems among women with multiple sclerosis. J Neurol Sci. 2013; 331(1-2):81-5. [DOI:10.1016/j.jns.2013.05.014] [PMID] [PMCID]
  9. Delaney KE, Donovan J. Multiple sclerosis and sexual dysfunction: A need for further education and interdisciplinary care. NeuroRehabilitation. 2017; 41(2):317-29. [DOI:10.3233/NRE-172200] [PMID]
  10. Asadpour E, Veisi S. [The effectiveness of emotionally focused couple therapy on sexual self-esteem and sexual function in women with multiple sclerosis (Persian)]. J Arak Uni Med Sci. 2017; 20(7):1-12. http://jams.arakmu.ac.ir/article-1-5174-en.html
  11. Aliakbari Dehkordi M. [Relationship between women sexual function and marital adjustment (Persian)]. Int J Behav Sci. 2010; 4(3):199-206. [Link]
  12. Abedi P, Jorfi M, Afshari P. [Evaluation of the health promotion lifestyle and its related factors in reproductive aged women in Ahvaz, Iran (Persian)]. J Community Health. 2015; 9(1):68-74. [Link]
  13. Abbasi M, Nabavi SM, Fereshtehnejad SM, Jou NZ, Ansari I, Shayegannejad V, et al. Multiple sclerosis and environmental risk factors: A case-control study in Iran. Neurol Sci. 2017; 38(11):1941-51. [DOI:10.1007/s10072-017-3080-9] [PMID]
  14. Liu XJ, Ye HX, Li WP, Dai R, Chen D, Jin M. Relationship between psychosocial factors and onset of multiple sclerosis. Eur Neurol. 2009; 62(3):130-6. [DOI:10.1159/000226428] [PMID] [PMCID]
  15. Khodaveisi M, Ashtarani F, Beikmoradi A, Mohammadi N, Mahjub H, Mazdeh M, et al. The effect of continuous care on the lifestyle of patients with multiple sclerosis: A randomized clinical trial. Iran J Nurs Midwifery Res. 2017; 22(3):225-31. [PMID]
  16. Tell A, Tavasoli E, Sharifirad G. [Evaluation of health promoting lifestyle and its relationship with quality of life in undergraduate students of Isfahan University of Medical Sciences (Persian)]. J Health Syst Res. 2010; 7(4):442-8. [Link]
  17. Pourghafari SS, Pasha GH, Attari Y. [A study of investigation of the effectiveness of life style components training according to individual psychology on marital satisfaction among married woman nurses of Dr. Ganjaviyan hospital in dezful (Persian)]. J Soc Psychol. 2009; 4(12):27-48. [Link]
  18. Karami J, Shalani B, Hoveyzi N. [Relationship between sexual self-esteem and sexual dysfunction with marital satisfaction in nurses hopitals Kermanshah City (Iran)(Persian)]. Qom Univ Med Sci J. 2017; 11(9):86-93. [Link]
  19. Pourmeidani S, Noori A, Shafti SA. [Relationship between life style and marital satisfaction (Persian)]. J Fam Res. 2014; 10(3):331-4. [Link]
  20. Mahmoodi Z. Life Style, Concepts and Approaches. Tehran: University of Rehabilitation Sciences and Social Welfare Press; 2014. [Link]
  21. Alpar ŞE, Şenturan L, Karabacak Ü, Sabuncu N. Change in the health promoting lifestyle behaviour of Turkish University nursing students from beginning to end of nurse training. Nurse Educ Pract. 2008; 8(6):382-8. [DOI:10.1016/j.nepr.2008.03.010] [PMID]
  22. Abedi P, Jorfi M, Afshari P, Fakhri A. How does health-promoting lifestyle relate to sexual function among women of reproductive age in Iran? Glob Health Promot. 2018; 25(3):15-21. [DOI:10.1177/1757975917706831] [PMID]
  23. Karimlou V, Charandabi SM, Malakouti J, Mirghafourvand M. Effect of counselling on health-promoting lifestyle and the quality of life in Iranian middle-aged women: A randomized controlled clinical trial. BMC Health Serv Res. 2019; 19(1):350. [DOI:10.1186/s12913-019-4176-0] [PMID] [PMCID]
  24. Wood FG, Alley E, Baer S, Johnson R. Interactive multimedia tailored to improve diabetes self-management. Nurs Clin North Am. 2015; 50(3):565-76. [DOI:10.1016/j.cnur.2015.05.009] [PMID]
  25. Mohaddes Ardebili F, Mehmandar M, Bozorgnejad M, Khalili E, Hosseini AF, Mobaderi T. [The eectiveness of multimedia self-care education on burn patients’ quality of life: An application of latent growth model (Persian)]. Razi J Med Sci. 2019; 25(12):33-42. [Link]
  26. Khakpoor S, Niknami S, Tavafian SS, Goodarzi A. [Traditional and modern teaching methods in improving eating behaviors of female elementary school students in Chabahar, Iran (Persian)]. J Mil Caring Sci. 2016; 3(1):41-7. [DOI:10.18869/acadpub.mcs.3.1.41]
  27. Emadi SR, Vakilifard AR, Kavosui AR. [The effect of constructivist multimedia software on the learning of basic Farsi words (Persian)]. J Teach Persian Speaker Lang. 2015; 4(10):47-64. [Link]
  28. Mazinani R, Akbari Mehr M, Kaskian A, Kashanian M. [Evaluation of prevalence of sexual dysfunctions and its related factors in women (Persian)]. Razi J Med Sci. 2013; 19(105):59-66. [Link]
  29. Dehghan-Nayeri N, Khakbazan Z, Ghafoori F, Nabavi SM. Sexual dysfunction levels in Iranian women suffering from multiple sclerosis. Mult Scler Relat Disord. 2017; 12:49-53. [DOI:10.1016/j.msard.2017.01.005] [PMID]
  30. Tavakol Z, Mirmolaei ST, Movahed Z. [The survey of sexual function relationship with sexual satisfaction in referred to Tehran South City health centers (Persian)]. Avicenna J Nurs Midwifery Care. 2011, 19(2):50-4. [Link]
  31. Sealed Envelope. Simple randomisation service’, Randomisation and online databases for clinical trials [Internet]. 2020 [Updated 2020 May]. Available from: [Link]
  32. Sanders AS, Foley FW, LaRocca NG, Zemon V. The multiple sclerosis intimacy and sexuality questionnaire-19 (MSISQ-19). Sexu Disabil. 2000; 18(1):3-26. [DOI:10.1023/A:1005421627154]
  33. Mohammadi K, Rahnama P, Mohammaditabar S, Montazeri A. [Validation of the Persian version of multiple sclerosis intimacy and sexuality questionnaire-19 (MSISQ-19) (Persian)]. Payesh. 2014; 13(5):602-7. [Link]
  34. Cohen J. Statistical power analysis for the behavioral sciences. New York: Routledge; 2013. [DOI:10.4324/9780203771587]
  35. Daneshfar F, Behboodi-Moghadam Z, Khakbazan Z, Nabavi SM, Nayeri N, Ghasemzadeh S, et al. The influence of Ex-PLISSIT (extended permission, limited information, specific suggestions, intensive therapy) model on intimacy and sexuality of married women with multiple sclerosis. Sex Disabil. 2017; 35(4):399-414. [DOI:10.1007/s11195-017-9482-z]
  36. Dasgupta R, Wiseman OJ, Kanabar G, Fowler CJ, Mikol D. Efficacy of sildenafil in the treatment of female sexual dysfunction due to multiple sclerosis. J Urol. 2004, 171(3):1189-93. [DOI:10.1097/01.ju.0000113145.43174.24] [PMID]
  37. Lúcio AC, D'Ancona CA, Lopes MH, Perissinotto MC, Damasceno BP. The effect of pelvic floor muscle training alone or in combination with electrostimulation in the treatment of sexual dysfunction in women with multiple sclerosis. Mult Scler.  2014; 20(13):1761-8. [DOI:10.1177/1352458514531520] [PMID]
  38. Mosalanejad F, Afrasiabifar A, Zoladl M. Investigating the combined effect of pelvic floor muscle exercise and mindfulness on sexual function in women with multiple sclerosis: A randomized controlled trial. Clin Rehabil. 2018; 32(10):1340-7. [DOI:10.1177/0269215518777877] [PMID]
  39. Ahani L, Chorami M, Sharifi T, Ghazanfari A, Adibi Sedeh I. The effect of mindfulness psych-educational group intervention on improving sexual function of women with multiple sclerosis. Prev Care Nurs Midwifery J. 2021; 11(4):35-45. [DOI:10.52547/pcnm.11.4.35]
  40. Giannantoni A, Proietti S, Giusti G, Gubbiotti M, Millefiorini E, Costantini E, et al. OnabotulinumtoxinA intradetrusorial injections improve sexual function in female patients affected by multiple sclerosis: Preliminary results. World J Urol. 2015, 33(12):2095-101. [DOI:10.1007/s00345-015-1578-4] [PMID]
  41. Ghasemi V, Nabavi SM, Simbar M, Ozgoli G, Majd HA, Mirshafaei MS, et al. The effect of sexual health promotion package on sexual life in women with multiple sclerosis: Designed based on the results of a mixed method study. Sex Disabil. 2021; 40:57-75. [DOI:10.1007/s11195-021-09697-w]
  42. Mahan LK, Raymond JL. Krause’s Food & The Nutrition Care Process, Iranian Edition E-Book. London: Elsevier Health Sciences UK; 2016. [Link]
  43. Pazokian M, Shaban M, Zakerimoghdam M, Mehran A, Sangelagi B. [A comparison between the effect of stretching with aerobic and aerobic exercises on fatigue level in multiple sclerosis patients (Persian)]. Qom Univ Med Sci J. 2013; 7(1):50-6. [Link]
  44. Looker T, Gregson O. Managing Stress [M Rezaei, M Zhekan,  Persian trans]. Mashhad: Atabak; 2009. [Link]
  45. Bolton R. People skills. Simon and Schuster [HR Sohrabi, A Hayat Roshanaei, Persian trans]. Tehran: Roshd; 2002. [Link]
  46. Badeleh A, Alinasab E, Rezazadeh HR. [The effectiveness of police multimedia training packages on students’ attitudes towards social security (Persian)]. J Soc Ord. 2020; 12(1):77-98. [Link]
Type of Study: Research | Subject: Midwifery
Received: 2021/09/29 | Accepted: 2022/04/21 | Published: 2022/05/1

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