TY - JOUR JF - IJN JO - IJN VL - 13 IS - 21 PY - 1999 Y1 - 1999/6/01 TI - Influence and com pars ion intravenous Diazepam with intravenous midazolam as premedication in anesthesia on the saturation of arterial blood oxygen (1992) TT - بررسی و مقایسه تاثیر دیازپام وریدی با میدازولام وریدی به عنوان پیش داروی بیهوشی بر چگونگی اشباع اکسیژن خون شریانی قبل از شروع عمل جراحی در بیماران ریسک یک تحت بیهوشی عمومی در اطاق عمل یکی از ... N2 -   This research, which is semi- experimental is focused on the influence and comparison intravenous diazepam   with intravenous midazolam as premedication in anesthesia on the saturation arterial blood oxygen before surgical   operation, "pan patients who are in risk one under general anesthesia in the operating rooms of the hospitals   affiliated to Iran University of Medical Sciences and Health services.   Purposes of research   A.General purposes:   1. Determine and compare the influence intravenous diazepam with intravenous midazolam as premedication in   anesthesia on the saturation arterial blood oxygen before surgical operation upon patients who are in risk one   under general anesthesia in the operating rooms of the hospitals affiliated to Iran University of Medical Sciences   and Health Services.   2 Recommendations in order to use findings in anesthesia.   3. Recommendations in order to follow up studies.   B.special aims:   1. Determine individual characteristics of patients.   2 Determine the influence of intravenous diazepam as premedication in anesthesia on the saturation arterial   blood f'.U}'gen before surgical procedure , upon patients who (Ire in risk one under general anesthesia in the operating   rooms of the hospitals affiliated to Iran University of Medical Sciences and Health services.   3. Determine influence of intravenous midazolam as premedication in anesthesia on the saturation arterial   blood oxygen before surgical operation upon patients who are in risk one under general anesthesia in the operating   rooms of the hospitals affiliated to Iran University of Medical Sciences and Health Services.   4. Comparsion of influence of intravenous diazepam with intravenous midazolam as premedication in   anesthesia on the saturation arterial blood oxygen before surgical operation, upon patients who are in risk one   under general anesthesia in the operating rooms of the hospitals affiliated of Iran University of Medical Sciences   and Health services.   Hypothesises of research:   I . Saturation arterial blood oxygen 5 minutes after injection of intravenous diazepam differed with saturation   arterial blood oxygen 5 minutes after injection of intravenous midazolam as premedication in anesthesia.   2 Saturation arterial blood oxygen 10 minutes after injection of intravenous diazepam differed with saturation   arterial blood oxygen 10 minutes after injection of intravenous midazolam as premedication in anesthesia upon   patients who are in risk one under general anesthesia.   3. Saturation arterial blood oxygen 15 minutes after injection of intravenous diazepam differed with saturation   arterial blood oxygen 15 minutes after injection of intravenous midazotam as premedication in anesthesia upon   patients who au in risk one under general anesthesia.   4. Saturation arterial blood oxygen before surgical operation after injection of intravenous diazepam differed   with saturation arterial blood oxygen before surgical operation after injection of intravenous midasolam as   premedication in anesthesia upon patients who are in risk one under general anesthesia.   The limitation out of control of researcher:   1. Because of different individual characteristics every one has different reactions to drugs, which can affect the   result of the research which is not under the control of the researcher.   2. Affected research sample with unknown disease somehow could influence the research result which is out of   researcher control:   3. Different pasimu, position mind could influence research results out o[ researcher control   There were 80 subjects used in thier research between the ages of 18 and 45 years old consistring of 37 women   and 43 men, 0.2 mg/IV/kg diazepam was injected to first group and D.ll5 mg/W /kg was injected to control group   before surgery.   Outcome and research result companion incase of intravenous diazepam influence with intravenous midazolam   as premedication on the saturation arterial blood oxygen before surgical operation, upon patients who art in risk   one under general anesthesia has shown that both drugs decrease the saturation arterial blood oxygen but this   reduction by midazolam is more pronounced.   The statistical t test shown the meaningful relationship between first and second groups , in the first 5 minutes after premedication injection SP - 12 EP - 18 AU - Momayez Siahkal, AD - UR - http://ijn.iums.ac.ir/article-1-1344-en.html ER -