Volume 24, Number 72 (October 2011)                   IJN 2011, 24(72): 67-77 | Back to browse issues page


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Hashemizadeh H, Jafarzadeh A, Broumand H. Risk Factors andthe Most Common Initial Symptoms of Acute Lymphoblastic Leukemia in Children. IJN. 2011; 24 (72) :67-77
URL: http://ijn.iums.ac.ir/article-1-1030-en.html

Senior Lecturer, Medical- Surgical Department, Quchan Branch, Islamic Azad University, Khorasan, Iran (*Corresponding Author) Tell: +98-0581-2201214 Email: Haydeh_h_z@yahoo.com
Abstract:   (5370 Views)

  Background: The factors involve in Leukemia are not fully understood. However, research has shown the relationship between this disorder and some risk factors. The aim of this study was to determine risk factors involved in acute lymphoblastic leukemia and its most prevalent clinical manifestations in children residing in Khorasan province.

  Materials and Methods: It was a case – control study. The adequate sample size was 100 cases and 400 controls. Controls were matched with cases regarding their sex, age and habitation. Data was collected by face to face interview with patients' mothers and the questionnaires were completed by the investigator. Data was analyzed by conditional logistic regression using SPSS-PC (v.14).

  Results: According to the findings of this study, maternal use of oral contraceptives, living in proximity to high voltage power lines, in-utero ionizing radiation exposure, pesticide exposure in fathers and paternal occupation and parental smoking had a significant relation with this type of cancer (p<0.05).the most prevalent mitial clinical manifestations were lethargy and weakness, fever, leg pain, cervical lymphadenopathy, bleeding, abdominal pain and cold symptoms respectively

  Conclusion: According to the results of this study, it seems that environmental factors play an important role in etiology of this kind of cancer. Knowledge abort this fact helps us to find appropriate ways to prevent this disease in children.

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Type of Study: Research | Subject: nursing
Received: 2012/02/13 | Accepted: 2014/08/25 | Published: 2014/08/25

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